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Mineralocorticoid receptor antagonists have an important role in the management of diuretic-resistant volume overload or treatment-resistant hypertension

Furthermore, the FAT domain of FAK has limited sequence similarity to other proteins contained in the proteome, and therefore direct FAT ligands are predicted to have a potential selectivity advantage over traditional ATP-competitive kinase domain inhibitors, which is supported by the kinome profiling of 2012 (Fig

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In vivo distribution and recognition of [ 68 Ga]Ga- LyP-1 in BLM-treated mice Mice that received BLM or saline were used to detect the in vivo distribution of [ 68 Ga]Ga-LyP-1 or [ 68 Ga]Ga-ARA at 1 h and 2 h after intravenous injection of radiolabeled peptides