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For athletes running other compounds or taking NSAIDs to manage pain, this is not a trivial benefit

Most patients describe the sensation as a brief pinch or mild sting, with only slight soreness or tenderness at the injection site that fades within a day

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Genetics 175 , 826 (2017)

[7] [9] These contraindications are based on known metabolic pathways, clinical case reports, and established pharmacological principles, and are supported by clinical guidelines and expert consensus

Intervertebral disk tissue engineering using biphasic silk composite scaffolds