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Slightly more nerdy answer: because peptides are small, they can bind directly to cell receptors and trigger specific biological effects

Jillee P
(78) investigated the combined effects of aerobic exercise and chicory extract on NAFLD

doi: 10.1126/science.1164680 104 DixonSJLembergKMLamprechtMRSkoutaRZaitsevEMGleasonCEet al

doi: 10.1289/ehp.9008

Notably, a greater proportion of women with endometriosis and IBS experienced symptom improvement following a low FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols) diet compared to women with IBS alone [95]
