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a proportion of patients with Parkinson's disease develop dementia Cognitive impairment also occurs in the Parkinson-plus syndromes of progressive supranuclear palsy and corticobasal degeneration (and the same underlying pathology may cause the clinical syndromes of frontotemporal lobar degeneration)

Jacob RA, Sotoudeh G

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The success of this single-hormone approach has paved the way for more complex multi-agonist drugs

10.1016/j.stem.2009.11.013 5 BarkerN.van EsJ