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Deficiency in GAMT activity has been associated with conditions such as epilepsy, mental retardation and pyrimidal movement disorders ( Ensenauer etal, 2004)

AOD-9604 and GLP-1 agonists like Semaglutide or Tirzepatide work through fundamentally different mechanisms with very different efficacy profiles

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However, the main short peptides that have been tested in vitro and that act on cells and tissues of the oral cavity are the focus of this systematic review

A native gene would enable knockout models, expression mapping and antibody validation

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