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The result is a significant boost in intracellular NAD+ levels, which in turn activates sirtuins (SIRT1) proteins known to regulate cellular health and metabolism

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Translating that directly to human research doses is complicated by the obese rodent model problems described earlier and the difference in metabolic rate scaling between species

Schlothauer T, Rueger P, Stracke JO, Hertenberger H, Fingas F, Kling L, et al

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