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RNS , reactive nitrogen species

Because cisplatin is a DNA-damaging agent and an inducer of apoptosis, it is reasonable to expect changes in HSPs in the development of cellular resistance to the drug

For example,: in mammals 1523 GST genes have been reported, 4061 genes in plants (although it can reach more than 300 genes in wheat species), a range of 3035 in insects and 115 genes in bacteria (Hao et al., 2021

Cognitive frailty not only affects the quality of life of older adults but also significantly increases the risk of severe adverse outcomes such as dementia and disability [2]

(2023) 9:e12877