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in addition to its crucial role in maintaining genomic stability and regulating inflammation, SIRT6 also directly deacetylates NAMPT, enhancing its activity and promoting NAD + synthesis via the salvage pathway

Although, rare, but it can also cause adverse effects on many organs including heart, lungs, muscles, skin and nerves too

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Hypertriglyceridemia: changes in the plasma lipoproteins associated with an increased risk of cardiovascular disease
