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Test before use Perform a patch test by applying a small amount behind your knee or inside your elbow

Although naturally occurring, it is the least stable of the four types of B12 outside the human body and does not translate well into a tablet-based supplement

Some of these benefits include: The crowding out of pathogenic species like yeast and pathogenic bacteria thereby promoting better microbiome diversity (8)

Furthermore, L-glutamine supports antioxidant defence mechanisms by enhancing glutathione synthesis and stimulating the expression of antioxidant enzymes, thereby helping to combat oxidative stress and manage reactive oxygen species (ROS) generated during periods of heigh stress [68]

With these considerations, there are approved health claims for both states of the vitamin: stable and fully oxidised folic acid, and reduced folate (Additional file 1)

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