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Pregnant women may require additional folate supplementation (as advised by health professionals) to prevent congenital neural tube defects such as spina bifida (Fig 3)

They are often recommended for individuals who struggle to absorb B12 from food or supplements, such as those with certain medical conditions or dietary restrictions

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BPC-157 addresses multiple concerns simultaneously for Tirzepatide users

A double-blind, placebo-controlled trial could be helpful in exploring these questions (of note, the authors of this paper are currently conducting a clinical trial with secondary and exploratory outcomes aimed to explore symptomatic benefits, NCT04584346)