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qRT-PCR was carried out using SYBR Premix qRT-PCR ExTaq II (Takara) and analyzed on a Bio-Rad CFX96 real-time PCR cycler (Bio-Rad, Netherlands)

doi: 10.1007/978-981-15-2156-0 55 HatzigS

This suggests that M2-polarized TAMs play a significant role in reinforcing chemoresistance in ovarian cancer ( Immunotherapy resistance Targeting the macrophage population to reprogram or enhance TAMs into an M1-polarized, CXCL10-secreting state offers a promising new therapeutic approach, particularly for ovarian cancer subtypes like clear cell carcinoma (CCC), which are often marked by immune exclusion and poor prognosis
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