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Importantly, treatment of DIO mice with our NNMT inhibitors did not impact food intake, but produced marked reductions in body weight, WAT mass, adipocyte size, and cholesterol levels with negligible toxicity or observable adverse effects

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And protein kinase A phosphorylates hormone-sensitive lipase, the enzyme that physically breaks triglycerides apart into free fatty acids and glycerol

There is no TSA to worry about, but temperature control becomes the primary concern, especially during summer months

This condition is encountered both in professional athletes and in people who engage in sports only recreationally or sporadically