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An ice pack applied prior to injection also helps to dull the sensation and ease discomfort
Intestinal ischemia/reperfusion: microcirculatory pathology and functional repercussions
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doi:10.1007/s00018-013-1539-2 ^ Petersen K.F., Dufour S., Cline G.W., Shulman G.I
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Furthermore, there is some evidence from a rodent model that translocator protein radioligand uptake may be influenced by exercise (67), which is another argument for the importance of including sedentary controls in studies of ME/CFS
