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Antidepressant active ingredients from herbs and nutraceuticals used in TCM: pharmacological mechanisms and prospects for drug discovery

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Some clinical trials have reported positive results with NAC, especially for negative symptoms, assessed with PANSS and the CGI, but not for 14,42 The benefits of NAC could be based on the regulation of glutamate homeostasis with NAC

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Advances in metabolite processing methods and metabolite identification tools, such as Bio-Transformer, are expected to further expand the number of annotated metabolites, enhancing the comprehensive coverage enabled by of metabolic databases (Djoumbou-Feunang et al., 2019

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