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Description
540 For diseases with complex etiologies, single-target drugs often struggle to interfere with the complete network regulation of the disease and tend to produce significant toxicity
(PubMed) Rochette L, Ghibu S, Richard C, Zeller M, Cottin Y, Vergely C
Mol Cell 2016;61:809-20
Not every site is offering the treatment for all three of the autoimmune diseases
Conversely, reduced ROS levels in macrophages and DCs compromise CD8 + T-cell activation due to impaired antigen processing (75, 76)
All of those things generate oxidative stress
