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13 Journal of Medicinal Chemistry (ACS)Bisubstrate inhibitors of NNMT with enhanced activity

The follow-up pivotal trial (METAOD006 / OPTIONS) enrolled a larger cohort and failed to replicate statistically significant weight loss, which led Metabolic Pharmaceuticals to halt the formal drug development program in 2007

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It's recommended for dogs, cats, horses, and livestock like camels, cows, goats, pigs, and sheep

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