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Aggregation is promoted by temperature fluctuations, mechanical agitation (shaking the vial vigorously), and freeze-thaw cycles

3.4.3 Mechanistic insights from preclinical modelsbarrier, immune, and neurotransmitter changes Rodent models of PTSD provide causal evidence that psychological trauma disrupts the MGBA, leading to microbiota alterations, compromised gut barrier integrity, immune activation and neurotransmitter imbalance
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