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The Journal of investigative dermatology , S0022-202X(21)02089-3

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Systematic reviews of clinical studies show that IV and oral glutathione have promising effects on skin lightening and oxidative balance, although more long-term data are still needed

Arsenic contamination of food and water is a problem in many parts of the world

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The recent discovery of the small molecule N6F11, which binds the tripartite region of Trim25 and promotes proteasome-degradation of GPX4 in pancreatic cancer cells, while sparing immune cells and the anti-tumoral response of the microenvironment, could represent a major clinical breakthrough for the use of GPX4 inhibitor/degrader [61]