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Advances in encapsulation technologies and novel drug delivery systems are constantly pushing the boundaries of what's possible for oral administration, aiming to bridge that bioavailability gap

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The primary preclinical evidence comes from mouse studies showing reduced body weight and adipose mass in diet-induced obese mice (2018), improved grip strength in aged mice (2024), and beneficial microbiome changes when combined with caloric restriction (2022)

B, Analytical technologies in the biomedical and life sciences 877, 587593 (2009)