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The undifferentiated human monomyelocyte PLB-985 and gp91 phox KO-PLB-985 (PLB-985-KO) cells [22, 23] were cultured in a complete medium RPMI 1640, supplemented with 1% P/S, and 10 % heat-inactivated FBS

Furthermore, disease models based on the transgenic expression of ALS-associated mutations in vivo have been used extensively to investigate ALS pathogenesis and motor neuron degeneration (Taylor et al., 2016)