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The Potential Role of Keap1-Nrf2 Pathway in the Pathogenesis of Alzheimer's Disease, Type 2 Diabetes, and Type 2 Diabetes-Related Alzheimer's Disease

c , Representative hematoxylin and eosin (H&E)-stained sections of major organs (heart, liver, spleen, lung, and kidney) collected 24 h post-injection from mice treated with TRAPmLuc (control) or TRAPmHPV revealed no apparent histopathological abnormalities, indicating minimal off-target tissue toxicity

The micro-CT images showed that BLM-induced pulmonary fibrosis was more severe in aged mice compared to the young when they received the same dose, i.e., larger area of regional consolidation, higher HU density, and less air volume in the lung (Fig

They scavenge active radicals to inhibit chain initiation and break chain propagation reactions

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Lancet 22:983984 Retsema J, Girard A, Schelky W, Manousos M, Anderson M, Bight G, Borovoy R, Brennan L, Mason R (1987) Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring macrolide with improved potency against Gram-negative organisms