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demonstrated that Erastin treatment in fibroblasts and fibrosarcoma cells robustly induced the conversion of LC3I to LC3II and the formation of GFP-LC3 puncta, which are definitive hallmarks of autophagy activation (49)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 73.Kelly MK, Wicker RJ, Barstow TJ, Harms CA

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Research from Russia and Eastern Europe, where DSIP has been studied more extensively than in the United States, has suggested the peptide may reduce withdrawal symptom severity and improve outcomes in opioid detoxification protocols

van Vught AJAH, Nieuwenhuizen AG, Veldhorst MAB, Brummer R-J, Westerterp-Plantenga MS