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266 The activation of Wnt signaling is negatively correlated with the atherosclerotic severity

Among natural products, phenolic compounds and alkaloids are multi-target drugs with the strongest antioxidant, anti-inflammatory effects, neurotrophic effects and have the potential of high efficiency and low toxicity against aging and age-related diseases (Kooshki et al., 2023)

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R 12 is H, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 3 -C 6 cycloalkyl, C 2 -C 7 heterocycloalkyl, C 6 -C 10 aryl, C 3 -C 9 heteroaryl, C 1 -C 6 alkylC 3 -C 6 cycloalkyl, C 1 -C 6 alkylC 6 -C 10 aryl, or C 1 -C 6 alkylC 3 -C 9 heteroaryl

These neuroinflammatory responses and disrupted redox processes are believed to play significant roles in the progression of neurological symptoms, including brain fog [34]