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Histological examination showed reduced liver necrosis and restored tissue morphology in transplanted mice

Iron is essential for retinal metabolism, but an excess of ferrous iron causes oxidative stress, which is one of the main mechanisms for the occurrence of ferroptosis (Youale et al., 2022)

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Unlike many antioxidants, the body has a dedicated transporter specifically for ergothioneine, highlighting its importance for cellular protection

Chronic IH was found to result in selective activation of inflammatory pathways mediated by the transcription factor NF-B rather than adaptive pathways dependent on HIF-1 both in HeLa cells [150] and human endothelial EA.hy926 cells [151]

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