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Overall bacterial density in rectal swabs at the time of critical care admission has been shown to be in independent predictor of extra-intestinal infections [74]

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Additional evidence for a protective role of GPx1 can be in many other disease models, including stroke [106109], and neurodegeneration caused by trauma [114, 115], neurotoxins [116], and AD [123, 124]

In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation

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