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This binding activated cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) signaling pathway, resulting in the translocation of aquaporin-2 (AQP2) from the vesicle to the apical plasma membrane and markedly increasing the water reabsorption of principal cells (123)

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Ingredient effects, dosages, and safety vary by individual, formulation, and context

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Animal species acquire this compound through two primary mechanisms: dietary consumption and internal biosynthetic processes

T-tubule remodeling in cardiomyocytes TMAO disturbed myocardial excitation-contraction coupling by inducing Ca 2+ dysfunction (103)