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Interestingly, in vitro studies show that intestinal epithelial cells express RGD-dependent integrins, which recognize the RGD motif found in many ECM molecules, such as fibronectin, to anchor to the ECM and control their position and fate

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[DOI] [PubMed] [Google Scholar] 180.Cao M., Sun C., He W., Wang P., Wang F

Treatment involves hydroxocobalamin injections for confirmed deficiency and lifestyle modification for fatty liver disease management

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Additionally, more and more studies have revealed the importance of MOTS-c in regulating obesity and diabetes (11, 12), longevity (13), and cardiovascular disease (14)