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Others reported that bone microstructural features were improved and bone resorption was slowed following the administration of l-carnitine in aging ovariectomized rats, due to the reduction in bone turnover [94]

10.5534/wjmh.17040 85 RoderfeldM

However, the supernatant of B

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Skroza 2012)

It was not until the development of an in-vitro carnitine uptake assay on cultured fibroblast, a clear-cut definitive diagnosis of CUD could be made.2 However, in-vitro functional assay has many limitations and the most obvious one is the unavailability of living fibroblast as fibroblast culture from skin biopsy is not a routine investigation that is readily available