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NBEAL2 was again strongly reduced for the Gata1-deficient mice that were previously described by others to display macrothrombocytopenia, defective megakaryopoiesis and reduced -granule proteins in MKs.313022 Female carriers of GATA1 variants are asymptomatic, and our earlier studies revealed skewed X inactivation and no mutant GATA1 RNA in platelets from the D218Y carrier, while the D218G carrier had mild skewing of X inactivation with the presence of the D218G mutation in platelet RNA.14 We also performed immunoblot analysis to compare NBEAL2 protein expression in platelets of female carriers of GATA1 D218G and D218Y

Thiol/disulfide homeostasis: A prognostic biomarker for patients with advanced non-small cell lung cancer

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GT is the main cellular-housekeeper enzyme by detoxifying the endogenous, exogenous substrates and xenobiotic compounds, in phase II detoxification [47]

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