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doi: 10.1186/s12935-024-03534-8
PMC 372862
(2006) have presented a newer model for the catalytic reaction in which Glu146 functions as a general base, accepting a proton from zinc-bound water and shuttling the proton to the leaving group facilitating breakdown of the tetrahedral intermediate
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Am J Physiol Gastrointest Liver Physiol 2009
Structurally, p40 phox consists of a PX, SH3, and PB1 domain
