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Hydrogen bonds between backbone amide NH and CO groups stabilize the -helix

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Importantly, NRF2 activation has been shown to alleviate PD-associated pathological hallmarks, specifically oxidative stress, mitochondrial dysfunction and neuroinflammation through expression of its target genes (Yang et al., 2022)

However, the degree centrality of Tbr1 +/ sociality-linked neurons was reduced by the cocktail treatment to levels comparable to those of WT mice (Fig 6C, middle)

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IFNgamma-mediated repression of system xc(-) drives vulnerability to induced ferroptosis in hepatocellular carcinoma cells