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The recommended dose is 3 tablets taken orally once daily with food, as glecaprevirs absorption is improved with food, for 8 weeks

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Following this, labeled PBP1b was added to the chamber at 100500 pM concentration and incubated with a reactive oxygen species scavenging cocktail consisting of SEC buffer with 5 mM protocatechuic acid (PCA), 0.1 M protocatechuate-3,4-dioxygenase (PCD), 1 mM ascorbic acid (AA), and 1 mM methyl viologen (MV) for 5 min

Shah JJ, Jakubowiak AJ, O'Connor OA, Orlowski RZ , Patterson M, Harvey D, Berger AJ, McDonald A, Mulligan G, Boral A, Pickard MD, Smith PG, Kuan HS, Walker R, Garnsey J, Burke K, Lonial S
