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Development of melanocytic nevi is related to the extent of sun exposure during the first two decades of life

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The expression of occludin, a protein involved in maintaining tight junction barrier properties, glial cell-derived neurotrophic factor (GDNF), associated with spermatogonial self-renewal, and transforming growth factor-beta (TGF-), implicated in injury repair processes, were analyzed in Sertoli cells

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The other groups were placed in a low-pressure environment simulated at 6000-m altitude in a low-oxygen chamber
