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A deposits give rise to microglia-mediated neuroinflammation (Thakur et al., 2023)

Collectively, these findings highlight that abiotic stress perception in plants involves highly dynamic and interconnected cellular signaling systems

CrossRef Comparative performance of insulin resistance-related indices in predicting adverse cardiovascular events among individuals with NAFLD and MASLD: a multi-center cohort study Yanqiu Huang, Yadan Xu, Chenghao Zhang, Wen Gu, Yue Li, Haojia Zhang, Tian Wang, Tangyi Su, Yangchen Lhamu, Yichen Chen, Liang Zhou, Lipeng Hao, Yang Yang, Hui Wang Cardiovascular Diabetology.2026;[Epub] CrossRef Routine biochemical indices for hepatometabolic stratification across the dysglycaemia spectrum: insulin resistance, fibrosis scores, and machine-learning integration Pedro Villafruela-Rodrguez-Manzaneque, Jordi Tortosa-Carreres, Antonio Sierra-Rivera, Manuela Morales-Garcs, Laura Sahuquillo-Frias, Goitzane Marcaida-Benito Advances in Laboratory Medicine / Avances en Medicina de Laboratorio.2026;[Epub] CrossRef -Glutamylcysteine restores glucolipotoxicity-induced islet -cell apoptosis and dysfunction via inhibiting endoplasmic reticulum stress Jinyi Zhou, Yingying Shi, Lishuang Zhao, Rong Wang, Lan Luo, Zhimin Yin Toxicology and Applied Pharmacology.2025

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This discrepancy can be attributed to elderly patients often being unable to tolerate intense chemotherapy, existing clinical comorbidities, and mutations that lead to resistance to systemic therapies [4,5]