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Abbreviations RCTs: Randomized clinical trials WMD: Weighted mean differences CI: Confidence intervals BMI: Body mass index GRADE: Grading of recommendations assessment, development, and evaluation PRISMA: Preferred reporting items for systematic reviews and meta-analyses PICO: Participant, intervention, comparison/control, and outcome ALT: Alanine transaminase ALP: Alkaline phosphatase AST: Aspartate transaminase CI: Confidence interval CRP: C-reactive protein GSH: Glutathione MDA: Malondialdehyde NO: Nitric oxide TAC: Total antioxidant capacity TNF-: Tumor necrosis factor- WMD: Weighted mean differences IL-6: Interleukin-6 MCP-: Monocyte chemoattractant protein-1 LCFAs: Long-chain fatty acids ROS: Reactive oxygen species PPAR: Peroxisome-activated receptors NF-B: Peroxisome-activated receptors NAFLD: Non-alcoholic fatty liver disease SD: Standard deviation SEs: Standard errors IQRs: Interquartile ranges hs-CRP: High-sensitivity CRP IG: Intervention group CG: Control group References 2008

In children, who have low dioxygenase activity, antibiotics containing pivalic acid, which binds carnitine, can cause carnitine deficiency, causing hypoglycaemia and encephalopathy

The areas of the body being treated

We might not offer it if they have a high risk for an eating disorder, or if they have a personal or family history of a specific thyroid cancer

So, do we even need to take it as a supplement

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