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Inhibitory effects of propolis granular A P C on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in A/J mice

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Wild-type p16 Ink4a restrains cell-cycle progression by abrogating cyclin-dependent kinase 4 (CDK4) or CDK6-mediated phosphorylation and inactivation of RB

10.3389/fnagi.2022.827263 [DOI] [PMC free article] [PubMed] [Google Scholar] Murray A

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In preclinical research, AOD9604 is primarily investigated for its selective lipolytic activitythe ability to stimulate fat breakdown (lipolysis) and inhibit fat synthesis (lipogenesis) without exhibiting the growth-promoting or diabetogenic effects of full-length growth hormone