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Further testing of individuals with ASD and CESLAC ruled-out secondary causes of fatty-acid oxidation deficiencies including multiple carboxylase deficiencies, zinc deficiency, elevated copper, generalized hyperlipidemia or hypercholesterolemia, and hypoglycemia

FOXO transcription factors are regulated by phosphorylation events, which induce FOXO nuclear exclusion thus inhibiting transcriptional activity (4)
Nat Commun 12(1):157 2021 PMC7794361 Chandrasekaran S, Simon R

PMID: 33150114

Ibrahim, C