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05 / Professional Administration Ensures safe and effective delivery by skilled practitioners

Clinical Benefits: Essential cofactor in fatty acid synthesis and energy metabolism Supports the integrity of keratin, the structural protein in hair and nails Involved in gluconeogenesis and blood glucose regulation Supports neurological function and nerve signalling May help address symptoms associated with biotin deficiency Intramuscular delivery ensures reliable absorption where oral intake is inadequate Your practitioner will assess whether biotin injections are clinically appropriate for your individual circumstances and recommend a treatment plan accordingly

Given the high frequency of musculoskeletal problems in individuals with clEDS (Supplementary Table 1), we propose that coordination of care for patients with clEDS lies with (pediatric) rheumatology and EDS services if available
Vendor technical sheets and primary studies report selectivity over related methyltransferases and enzymes of the NAD salvage pathway [1,6,7]
Technically yes, but the risk profile changes significantly
