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Low dose arabinosyl cytosin (LD ARA C) in hematologic malignancies and myelodysplastic syndromes (MDS)

High-dose formulations may overwhelm the body's absorption capacity

Zanassi, P., Paolillo, M., Montecucco, A., Avvedimento, E

Although these mice have normal CoQ levels in most of the tissues, they show a reduced level of MCLK1 protein (approximately 2-fold), reduced ROS levels, decreased oxidative stress and decreased oxidative damage, and their life span is 1530% longer than wild-type mice [137,139,140]