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Notably, a trial involving 64 patients with NASH showed substantial reductions in ALT and AST levels after just eight weeks of treatment with 210 mg/day of silymarin [12]
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Qu X, Zhang X, Yao J, et al

Instead of quitting cold turkey, some go with lower doses or alternate-day usesort of a middle ground to hold onto a few perks without full-on daily supplementation

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These effects included neuroprotection, growth promotion, antioxidant activity, and stimulation of biogenesis of mitochondria (Yamada et al., 2020)
