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Association between dietary choline and betaine intake and 10.6-year cardiovascular disease in adults

mTORC2 and SGK-1 also mediates the lipid metabolism in the intestine by controlling the activity of the PQM-1 transcription factor coupled to the hypodermal microRNA (miRNA) pathways, thereby facilitating the inter tissue transport of the fat reserves from somatic cells to the germline [117]

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Thus, characterization of any of these quaternary amine-binding transcription factors will provide crucial understanding of ligand binding and, by homology, present likely binding residues in their respective paralogues