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Furthermore, the diffusion coefficient can be used to calculate the hydrodynamic (Stokes) radius R h (or R S , which is the radius of the equivalent hydrodynamic sphere) of a protein using the Stokes-Einstein equation relating the diffusion of a spherical particle in a fluid to its size and the properties of the fluid

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Signs to reassess your protocol: If shedding has not decreased by week 8 and no vellus hairs are visible by week 16, consider escalating