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JAK inhibitors, such as Baricitinib and Tofacitinib, are small molecule drugs that hinder neutrophil migration and ROS generation by suppressing the secretion of inflammatory factors (68)

The diet is characterized by a depletion of carbohydrates which in turn place the body in a state

BDNF has a neuroprotective role against the pathogenesis of AD by reducing the expression and the activity of -secretase, thereby inhibiting the amyloidogenic pathway and reducing neurotoxic A formation in transgenic mice (Evans et al., 2011)

In addition, this is also promoting efforts to better comprehend the implication of the association between metabolism and NBD on the use of both traditional and emerging drugs generally used for T2DM and MetS to also treat conditions that up to now were only therapeutically approached from a neurologists perspective

doi: 10.1016/j.cell.2006.02.015 58 FacchinSBertinLBonazziELorenzonGDe BarbaCBarberioBet al

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