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doi: 10.1016/0041-008X(75)90275-6

However, researchers have proposed that the activation of Nrf2 plays a major role in the antioxidant mechanism for counteracting oxidative stress in neuropsychiatric conditions, mediated by both exogenous and endogenous antioxidants (85)

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37 , the C8-hydrocarbon chain conjugated compounds used in our study are characterized by a good lipophilicity with ready release into the cell

In 2015, however, we reported the surprising observation that mice in which all hepatocytes are constitutively TrxR1/Gsr-null are long-term viable and sustain relatively normal hepatic activities [107]