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Other documented adverse effects include decreased appetite (which contributes to the therapeutic effect), fatigue, injection site reactions, dizziness, and modest increases in heart rate (typically 2-4 beats per minute)

Ultimately, the choice of protocol is up to the lead researcher

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A preliminary study evaluating diabetic peripheral neuropathy has demonstrated that targeted supplementation with these active B-vitamins (along with pyridoxal 5'-phosphate) can actually increase epidermal nerve fiber density, meaning the nerves physically begin to regrow and heal, leading to a reduction in pain and paresthesia

Rhonda: I started out coming out in the public this was like 2014