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Although VEGF-D is a potential biomarker for ramucirumab in colorectal and hepatocellular carcinoma, earlier studies did not identify it as a useful biomarker for patients with GC (156)

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The peptide incorporates specific amino acid substitutions that make it resistant to dipeptidyl peptidase-4 (DPP-4), the enzyme primarily responsible for degrading natural GHRH

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