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PRDX-2 is also involved in the hormetic response leading to lifespan extension, where worms treated with metformin, the antihyperglycemic drug used in the treatment of type II diabetes, led to an increase in endogenous levels of H 2 O 2 [180]
SOD also prevents this detrimental event
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This finding may not be as specific in oliguric or anuric patients
Since plasma contains GGH activity, any polyglutamate that is released into plasma would be hydrolyzed into the monoglutamate
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