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Simultaneously, mitochondria also produce oxygen free radicals, called superoxide (O 2 ), non-enzymatically, which interacts with other moieties and generate reactive oxygen species (ROS), such as hydrogen peroxide (H 2 O 2 ), peroxynitrite (ONOO), and hydroxyl radical (OH )

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Selectivity remained high when using the longer trigger sequences, with a greater than 100-fold preference observed for CYRANO over its seed-only counterpart (Fig

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2007;28(3 Suppl):S40329

DNMT3A governs tyrosine kinase inhibitors responses through IAPs and in a cell senescence-dependent manner in non-small cell lung cancer