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, Bone homeostasis in growth hormone receptor-null mice is restored by IGF-I but independent of Stat5

Defects in regulatory T cells (Tregs) and increased expression of inflammasome components further amplify sensitivity to thyroid autoantigens
Prescription retinoid creams are available for treating hyperpigmentation

The recommended phase 2 dose (RP2D) for cabozantinib was 40 mg daily and the trial was expanded to a phase II multi-cohort, multi-center trial of 117 patients (Saeed et al., 2023)

Moreno-Montanes, J., Bleau, A
