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Ferroptosis, an iron-dependent form of cell death, is one such example in which excess iron triggers the accumulation of lipid peroxides in membranes, leading to programmed cell death

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Compounds like hypericin further suppress MMP3, MMP13, and ADAMTS5 expression in response to TNF, thereby preserving ECM integrity and restricting tumor cell access to metabolic resources [218]

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The protein can therefore be used as an antigen in immunoassays to differentiate between the two viruses

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